Chapter 2608 [2608] Such a Boss

While eating, I chatted with Teacher Tan about scientific research.

Teacher Tan is an expert in laparoscopy, an expert in general surgery, and an oncologist in digestive tract and gastrointestinal surgery. Mr. Tan's traditional surgery is as top-notch as laparoscopic surgery, and his extraoperative treatment plan for tumor patients is also first-rate.

It would be ridiculous to imagine that the scope of academic research Mr. Tan can do is limited to laparoscopy. For example, Brother Immortal rarely performs heart transplants, but he does research on assistive devices for end-stage cardiac treatment.

For surgeons, conducting scientific research and performing surgery is an advantage, which is reflected in the fact that they can conduct research on various operations. On the other hand, in the field of basic disciplines, surgeons have advantages, which mainly refers to the advantages of pathological specimens obtained by surgeons.

It is too easy for surgeons to capture surgical pathology specimens of various patient tumors during surgery. Unlike other departments, it is very difficult to get a pathological specimen that one wants. The specimens obtained by endoscopy are limited in scope, far less than those obtained by surgery. In this way, you will find that surgeons who engage in basic research are even better than shoulder physicians and pathologists.

Teacher Tan happens to be such a boss.

Specifically speaking of the research topic of Mr. Tan, it can be said that after entering the 21st century, a large class of star anti-tumor drugs is well-known: targeted drugs.

Targeted drugs are like shooting arrows aiming at tumors. Compared with chemotherapeutic drugs, they are like spraying pesticides when attacking tumors. They are highly accurate and avoid harming human healthy tissues. They are warmly welcomed by doctors and patients. The advantage of targeted drugs lies in accuracy, and the accuracy of targeted drugs is based on the target point. Finding the target point of targeted drugs has naturally become the top priority of researchers.

The study of targets is essentially inseparable from the study of tumor pathogenesis.

The pathogenesis of tumors is intricate, and there are many links and substances involved in the pathogenesis of tumors, all of which can be targeted in theory. For example, the most common substance receptors, transporters, enzymes, ion channels, genes, etc., many of which are basic topics that have been studied. Here is a relatively new research topic that was discovered and proposed in recent years, called microRNA.

Tiny RAN, to understand it simply, can be said to be a substance like intestinal flora. A good microRNA can inhibit tumor tissue after being absorbed by humans. Bad microRNAs can promote the growth of tumor tissue. According to this principle, if medical oncology studies the former, it can be made into a tumor suppressor. If you want to deal with the bad things behind, the targeted drug that makes a "sudden" attack is the most suitable.

It is found in medicine that killing tumors is worse than suppressing them. According to the information Xie Wanying knows from people who come back from the future, how cutting-edge the microRNA targeting drug is, it belongs to the new trend of the future targeted drug.

In any case, as mentioned earlier, to make a targeted drug, you must first find the target, and to make an RNA-targeted drug, you must find out the microRNA. Teacher Tan’s key topic is the study of colon cancer microRNA, and a brand new microRNA was discovered in a wide range of colon cancer specimens, which can theoretically become the target of a new targeted drug for colon cancer The key areas at the forefront of scientific research.

Teacher Tan's research project is so cutting-edge, Xie Wanying must say that she can't dictate what the teacher's research is.