Chapter 564 Toxin

"The surprise is that this is the most amazing thing in the world,

It is indescribable, difficult to fathom, and elusive.

Medical accidents, traffic accidents, sudden illnesses, food poisoning, falling objects from heights, fires, drownings, electric shocks...

Human life is so fragile,

A glass of water, an icicle, a chopstick, a fork, or even a nut can be enough to kill someone.

There are so many things that people have to face every day in modern life, and the possible ways to die are even more bizarre and gaudy than those shown in the movie "Death" or the TV show "1000 Ways to Die". "

The young man spread his hands and said with a smile, "Death is the destination of everyone, and it is also the fairest thing in the world.

If a murder case is shocking and outrageous, it will be recorded, and countless people will work together to track down the case and investigate the truth behind it.

An accidental death is associated with sadness, helplessness, and sometimes a bit of black humor.

Similarly, no one cares about persistence on the opposite side of accidental death, not even the media that pursues traffic - this is an accident and a helpless fate.

And I am responsible for creating accidents. "

Perhaps because this statement was self-praising, the smile on the young man's face was a little shy, "As time goes by, I am getting better and better at this aspect of things.

Even if the entire accident process is shown to the world in its entirety, no one can find the complete context of the story before the incident ends.

Just like a world-class magician, or a ruthless criminal conspiracy scholar in reasoning. "

——————

"Sister Lan, do you suspect that someone is chasing these criminals?"

"Um."

Wei Linglan nodded, looked at Chu Yin who was looking through the information, and nodded, "These cases are very ordinary, but I always feel that something is not normal.

I'm not an expert in this field, and the score in the criminal investigation course in the bureau is not very high.

You are smarter, see if there is any problem here. "

Chuyin said "yes" to the doctor, took a sip of the coke that was left on the ice, and stared at the information intently.

"Huang Yuanwei, male, 46 years old, driver, used to be a liaison in a criminal gang before.

One morning the summer before last year, while driving to Linshi, he suddenly felt that his breathing was becoming more and more difficult, and his throat and chest were tight.

There was constant pinprick pain in my fingertips, my palms could barely hold the steering wheel, and the road scene in front of me began to appear double.

For safety reasons, he immediately went to the hospital for treatment after barely driving off the highway.

When he arrived at the emergency department, his condition was already very bad. His complexion was sickly red, he was breathing heavily, and his chest was rising and falling. However, the physical and neurological examination results were relatively normal.

Considering that yesterday he was on a business trip and ate local food, and combined with his previous history of allergies,

The doctor thought this was a common allergy symptom, so he gave him the anti-allergic drug diphenhydramine - this drug has the effect of antihistamine H1 receptors, can inhibit the central nervous system, and is suitable for allergic diseases of the skin and mucous membranes, such as urticaria. , hay fever, allergic rhinitis, etc.

Histamine is an active amine compound that exists in mast cells and also in mucosal tissues such as lungs, liver, and stomach.

When the body detects an allergen, it releases histamine.

As a chemical conductor, histamine binds to receptors on vascular smooth muscle, causing blood vessels to dilate and produce local edema.

It also causes the tracheal smooth muscles of the lungs to contract, causing respiratory tract stenosis and difficulty breathing.

Blood pressure decreases and heartbeat increases.

The doctor used diphenhydramine to block histamine and gave Huang Yuanwei epinephrine to constrict his dilated blood vessels.

If he has allergies, this should work.

However, after several hours of observation, Huang Yuanwei's condition did not improve. He still felt uncomfortable and claimed that his stomach began to burn, and even taking oral antacids did not help.

Then, he felt his throat became tight and swollen, unable to speak or swallow, his heartbeat increased rapidly, and his eyelids drooped.

The doctor immediately gave him various examinations including MRI, but the examination results showed no problem.

Huang Yuanwei's condition continues to deteriorate at a strange speed.

His facial and throat muscles were paralyzed, he could not speak, he could not move his hands and feet, and his eyelids were drooped and unable to open. He could only use a respirator to help him breathe.

The most terrifying thing is that his will is still clear,

He could clearly feel that he was losing control of all his muscles little by little.

He could clearly feel that his body was becoming paralyzed.

He lost his life before doctors could provide further treatment.

It was not until his death that doctors understood the cause of his death.

His acute muscle paralysis was not a problem with his brain or spine, because the paralysis throughout his body was very balanced, even, and synchronized.

Nor could it be a viral infection of the nerves—viruses such as polio, which can cause general paralysis, can send patients into a fever that lasts for days before causing muscle paralysis.

Therefore, there can only be something wrong with the neuromuscular joint.

Motor neurons located in some nerve nuclei in the anterior horn of the spinal cord and brainstem send out nerve fibers to the muscles. The nerve fibers branch off into dozens or hundreds of branches at the muscle fibers.

Each branch terminates on a muscle fiber, forming a one-to-one neuromuscular junction.

The neuromuscular junction transmits signals from nerve fibers to muscle fibers, causing muscles to contract. If the neuromuscular junction is interrupted, it will lead to muscle atrophy and paralysis. "

Chuyin frowned and said, "And what causes neuromuscular joint failure is..."

"Botulinum toxin."

The young man smiled and said to the old woman: "Look, the whole process of muscle movement.

Instructions are sent from the nerve center,

transmit nerve impulses to axon terminals,

The protruding cells in the presynaptic membrane are stimulated to release neurotransmitters such as acetylcholine, which diffuse into the synaptic cleft and bind to receptors on the muscle membrane, triggering muscle contraction.

Botulinum toxin binds to the presynaptic membrane of cholinergic neurons, undergoes endocytosis, and forms an acidic vesicle wrapping the toxin molecules, which is retained at the end of the presynaptic membrane of motor neurons.

Blocks the release of the normal neurotransmitter acetylcholine,

This causes muscle paralysis.

I have been observing secretly, and sure enough, it was as I expected after the official announcement.

Following the botulinum toxin ingested by Huang Yuanwei, we found the food he ate in the restaurant yesterday - a ham originally packed in a can.

And the owner of that restaurant happened to be a murder suspect who had been on the run for many years.

For botulinum toxin to be produced in canned food, the temperature and pH value of the external environment must be completely suitable.

It was a perfect, regrettable accident. "

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